A Case-Control Study to Add Volumetric or Clinical Mammographic Density into the Tyrer-Cuzick Breast Cancer Risk Model.

ABSTRACT:

Background

Accurate breast cancer risk assessment for women attending routine screening is needed to guide screening and preventive interventions. We evaluated the accuracy of risk predictions from both visual and volumetric mammographic density combined with the Tyrer-Cuzick breast cancer risk model.

Methods

A case-control study (474 patient participants and 2243 healthy control participants) of women aged 40-79 years was performed using self-reported classical risk factors. Breast density was measured by using automated volumetric software and Breast Imaging and Reporting Data System (BI-RADS) density categories. Odds ratios (95% CI) were estimated by using logistic regression, adjusted for age, demographic factors, and 10-year risk from the Tyrer-Cuzick model, for a chang

SUBMITTER: Brentnall AR 

PROVIDER: S-EPMC6690422 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature