Bis(mefloquinium) butane-dioate ethanol monosolvate: crystal structure and Hirshfeld surface analysis.

ABSTRACT: The asymmetric unit of the centrosymmetric title salt solvate, 2C₁₇H₁₇F₆N₂O⁺· C₄H₄O₄ ^2-·CH₃CH₂OH, (systematic name: 2-{[2,8-bis-(tri-fluoro-meth-yl)quinolin-4-yl](hy-droxy)meth-yl}piperidin-1-ium butane-dioate ethanol monosolvate) comprises two independent cations, with almost superimposable conformations and each approximating the shape of the letter L, a butane-dioate dianion with an all-trans conformation and an ethanol solvent mol-ecule. In the crystal, supra-molecular chains along the a-axis direction are sustained by charge-assisted hy-droxy-O-H⋯O(carboxyl-ate) and ammonium-N-H⋯O(carboxyl-ate) hydrogen bonds. These are connected into a layer

SUBMITTER: Wardell JL 

PROVIDER: S-EPMC6690461 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature