Crystal structures of two new isocoumarin derivatives: 8-amino-6-methyl-3,4-diphenyl-1H-isochromen-1-one and 8-amino-3,4-diethyl-6-methyl-1H-isochromen-1-one.

ABSTRACT: The title compounds, 8-amino-6-methyl-3,4-diphenyl-1H-isochromen-1-one, C₂₂H₁₇NO₂, (I), and 8-amino-3,4-diethyl-6-methyl-1H-isochromen-1-one, C₁₄H₁₇NO₂, (II), are new isocoumarin derivatives in which the isochromene ring systems are planar. Compound II crystallizes with two independent mol-ecules (A and B) in the asymmetric unit. In I, the two phenyl rings are inclined to each other by 56.41 (7)° and to the mean plane of the 1H-isochromene ring system by 67.64 (6) and 44.92 (6)°. In both compounds, there is an intra-molecular N-H⋯O hydrogen bond present forming an S(6) ring motif. In the crystal of I, mol-ecules are linked by N-H⋯π inter-actions, forming chains along the b-axi

SUBMITTER: Syed Abuthahir S 

PROVIDER: S-EPMC6690470 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature