Co-infection of vvMDV with multiple subgroups of avian leukosis viruses in indigenous chicken flocks in China.

ABSTRACT:

Background

In China, although the ALV eradication program and the MD vaccination strategy greatly reduce the disease burdens caused by the infection of ALV and MDV, the frequent emergence of novel ALV-K or vvMDV in the vaccinated chicken flock challenges the current control strategies for both diseases.

Results

In Guangdong Province, an indigenous chicken flock was infected with neoplastic disease. Hematoxylin-eosin staining of the tissues showed the typical characteristics of MDV and classical ALV infection. The PCR and sequencing data demonstrated that the identified MDV was clustered into a very virulent MDV strain endemic in domestic chickens in China. Moreover, subgroups ALV-A and ALV-K were efficiently recovered from two samples. The full genome sequence revealed that

SUBMITTER: Li T 

PROVIDER: S-EPMC6691527 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature