Current practice and awareness of pediatric off-label drug use in Shanghai, China -a questionnaire-based study.

ABSTRACT:

Background

Off-label drug use is widespread in pediatric drug treatment, and the implementation of guidelines on this topic remains challenging. The objective of this study was to evaluate current practice and awareness of healthcare professionals towards pediatric off-label drug use, as well as the barriers to guideline implementation among pediatric healthcare professionals in Shanghai, China.

Methods

A validated questionnaire was issued to representatives of pediatricians, pharmacists, nurses and administrators from hospitals with pediatric qualification in Shanghai.

Results

A total of 679 completed questionnaires from 69 hospitals were included in the analysis. Nearly half (47.9%) of the pediatricians acknowledged that they had prescribed off-label drugs. Most (88

SUBMITTER: Mei M 

PROVIDER: S-EPMC6691537 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature