MARPLE, a point-of-care, strain-level disease diagnostics and surveillance tool for complex fungal pathogens.

ABSTRACT:

Background

Effective disease management depends on timely and accurate diagnosis to guide control measures. The capacity to distinguish between individuals in a pathogen population with specific properties such as fungicide resistance, toxin production and virulence profiles is often essential to inform disease management approaches. The genomics revolution has led to technologies that can rapidly produce high-resolution genotypic information to define individual variants of a pathogen species. However, their application to complex fungal pathogens has remained limited due to the frequent inability to culture these pathogens in the absence of their host and their large genome sizes.

Results

Here, we describe the development of Mobile And Real-time PLant disEase (MARPLE) diag

SUBMITTER: Radhakrishnan GV 

PROVIDER: S-EPMC6691556 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature