Effect of In-Utero Antibiotic Exposure on Childhood Outcomes: Methods and Baseline Data of the Fetal Antibiotic EXposure (FAX) Cohort Study.

ABSTRACT:

Background

The widespread use of antepartum and intrapartum antibiotics has raised concerns about the possible disruption of the child's gut microbiota and effects on the maturation from the infant to the adult microbiome. The Fetal Antibiotic EXposure (FAX) study provides a cohort to examine the association between in-utero exposure to antibiotics and adverse childhood outcomes including body weight, atopic diseases, and autism spectrum disorders and to investigate the role of other potential factors mitigating or moderating the risk for adverse outcomes.

Objective

The aim of this paper was to describe the methods, cohort characteristics, and retention of infants included in the study cohort.

Methods

For this retrospective cohort study, we included children born in K

SUBMITTER: Koebnick C 

PROVIDER: S-EPMC6691671 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature