Optimal timing of influenza vaccine during pregnancy: A systematic review and meta-analysis.

ABSTRACT:

Background

Pregnant women have an elevated risk of illness and hospitalisation from influenza. Pregnant women are recommended to be prioritised for influenza vaccination during any stage of pregnancy. The risk of seasonal influenza varies substantially throughout the year in temperate climates; however, there is limited knowledge of how vaccination timing during pregnancy impacts the benefits received by the mother and foetus.

Objectives

To compare antenatal vaccination timing with regard to influenza vaccine immunogenicity during pregnancy and transplacental transfer to their newborns.

Methods

Studies were eligible for inclusion if immunogenicity to influenza vaccine was evaluated in women stratified by trimester of pregnancy. Haemagglutination inhibition (HI) titres

SUBMITTER: Cuningham W 

PROVIDER: S-EPMC6692549 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature