Safety Aspects, Tolerability and Modeling of Retinofugal Alternating Current Stimulation.

ABSTRACT:

Background

While alternating current stimulation (ACS) is gaining relevance as a tool in research and approaching clinical applications, its mechanisms of action remain unclear. A review by Schutter and colleagues argues for a retinal origin of transcranial ACS' neuromodulatory effects. Interestingly, there is an alternative application form of ACS specifically targeting α-oscillations in the visual cortex via periorbital electrodes (retinofugal alternating current stimulation, rACS). To further compare these two methods and investigate retinal effects of ACS, we first aim to establish the safety and tolerability of rACS.

Objective

The goal of our research was to evaluate the safety of rACS via finite-element modeling, theoretical safety limits and subjective report.

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SUBMITTER: Haberbosch L 

PROVIDER: S-EPMC6692662 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature