Case-crossover analysis of short-term particulate matter exposures and stroke in the health professionals follow-up study.

ABSTRACT:

Background

Stroke is a leading cause of morbidity and mortality in the United States. Associations between short-term exposures to particulate matter (PM) air pollution and stroke are inconsistent. Many prior studies have used administrative and hospitalization databases where misclassification of the type and timing of the stroke event may be problematic.

Methods

In this case-crossover study, we used a nationwide kriging model to examine short-term ambient exposure to PM₁₀ and PM_2.5 and risk of ischemic and hemorrhagic stroke among men enrolled in the Health Professionals Follow-up Study. Conditional logistic regression models were used to obtain estimates of odds ratios (OR) and 95% confidence intervals (CI) associated with an interquartile range (IQR

SUBMITTER: Fisher JA 

PROVIDER: S-EPMC6692897 | biostudies-literature | 2019 Mar

REPOSITORIES: biostudies-literature