Pregnancy duration and endometrial cancer risk: nationwide cohort study.

ABSTRACT:

Objective

To explore the association between pregnancy duration and risk of endometrial cancer.

Design

Nationwide register based cohort study.

Setting

Denmark.

Participants

All Danish women born from 1935 to 2002.

Main outcome measures

Relative risk (incidence rate ratio) of endometrial cancer by pregnancy number, type, and duration, estimated using log-linear Poisson regression.

Results

Among 2 311 332 Danish women with 3 947 650 pregnancies, 6743 women developed endometrial cancer during 57 347 622 person years of follow-up. After adjustment for age, period, and socioeconomic factors, a first pregnancy was associated with a noticeably reduced risk of endometrial cancer, whether it ended in induced abortion (adjusted relative risk 0.53 (95% confi

SUBMITTER: Husby A 

PROVIDER: S-EPMC6693051 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature