Bidirectional chemotherapy allowing surgery and HIPEC for malignant peritoneal mesothelioma.

ABSTRACT:

Background

This case report aims to describe the impact of the bidirectional chemotherapy (BDC) on resecability for initially unresectable malignant peritoneal mesothelioma (MPM).

Methods

We report a case of 55-year-old male with the diagnosis of initially unresecable MPM. The BDC combined intravenous (IV) chemotherapy (Cisplatin-Pemetrexed) and intra peritoneal (IP) chemotherapy (Cisplatin). The response to chemotherapy was assessed by CT - scan and laparoscopy.

Results

Initial evaluation classed the disease as unresecable with PCI at 39. At the reevaluation, CT - scan and laparoscopy showed a macroscopic response, allowing surgery consisting of cytoreductive surgery and hyperthermic intra peritoneal chemotherapy (Doxorubicin and Cisplatin).

Conclusions

BDC (I

SUBMITTER: Noiret B 

PROVIDER: S-EPMC6693479 | biostudies-literature | 2019 Jun

REPOSITORIES: biostudies-literature