Radiomic features from MRI distinguish myxomas from myxofibrosarcomas.

ABSTRACT:

Background

Myxoid tumors pose diagnostic challenges for radiologists and pathologists. All myxoid tumors can be differentiated from each other using fluorescent in-situ hybridization (FISH) or immunohistochemical markers, except for myxomas and myxofibrosarcomas. Myxomas and myxofibrosarcomas are rare tumors. Myxomas are benign and histologically bland, whereas myxofibrosarcomas are malignant and histologically heterogenous. Because of the histological heterogeneity, low grade myxofibrosarcomas may be mistaken for myxomas on core needle biopsies. We evaluated the performance of T1-weighted signal intensity (T1SI), tumor volume, and radiomic features extracted from magnetic resonance imaging (MRI) to differentiate myxomas from myxofibrosarcomas.

Methods

The MRIs of 56 patient

SUBMITTER: Martin-Carreras T 

PROVIDER: S-EPMC6694512 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature