Prognostic value of frailty in elderly patients with acute coronary syndrome: a systematic review and meta-analysis.

ABSTRACT:

Background

Frailty is common and associated with poorer outcomes in the elderly, but its prognostic value in acute coronary syndromes (ACS) requires clarification. We thus undertook a systematic review and meta-analysis to evaluate the relationship between frailty and poor prognosis in patients with ACS.

Methods

We systematically searched PubMed, Embase to find literatures which studied the prognostic value of frailty in elderly patients with ACS. Our main endpoints were the all-cause mortality, cardiovascular disease (CVD), major bleeding and readmissions. We pooled studies using random-effect generic inverse variance method, and conducted three pre-specified subgroup analyses.

Results

Of 1216 identified studies, 15 studies were included in our analysis. Compared wit

SUBMITTER: Dou Q 

PROVIDER: S-EPMC6694517 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature