Disentangling stability and flexibility degrees in Parkinson's disease using a computational postural control model.

ABSTRACT:

Background

Impaired postural control in Parkinson's disease (PD) seriously compromises life quality. Although balance training improves mobility and postural stability, lack of quantitative studies on the neurophysiological mechanisms of balance training in PD impedes the development of patient-specific therapies. We evaluated the effects of a balance-training program using functional balance and mobility tests, posturography, and a postural control model.

Methods

Center-of-pressure (COP) data of 40 PD patients before and after a 12-session balance-training program, and 20 healthy control subjects were recorded in four conditions with two tasks on a rigid surface (R-tasks) and two on foam. A postural control model was fitted to describe the posturography data. The model comp

SUBMITTER: Rahmati Z 

PROVIDER: S-EPMC6694532 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature