The economic impact of substandard and falsified antimalarial medications in Nigeria.

ABSTRACT:

Introduction

Substandard and falsified medications pose significant risks to global health. Nearly one in five antimalarials circulating in low- and middle-income countries are substandard or falsified. We assessed the health and economic impact of substandard and falsified antimalarials on children under five in Nigeria, where malaria is endemic and poor-quality medications are commonplace.

Methods

We developed a dynamic agent-based SAFARI (Substandard and Falsified Antimalarial Research Impact) model to capture the impact of antimalarial use in Nigeria. The model simulated children with background characteristics, malaria infections, patient care-seeking, disease progression, treatment outcomes, and incurred costs. Using scenario analyses, we simulated the impact of substa

SUBMITTER: Beargie SM 

PROVIDER: S-EPMC6695148 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature