Is atopic sensitization associated with indicators of early vascular ageing in adolescents?

ABSTRACT:

Background

Chronic systemic inflammation accelerates early vascular ageing. Atopic sensitization and allergic diseases may involve increased inflammatory activity. This study aimed to assess whether atopic sensitization and allergic diseases were associated with altered vascular biomarkers in Norwegian adolescents.

Methods

Distensibility coefficient of the common carotid arteries, carotid intima-media thickness and atopic sensitization (serum total and specific IgEs) were assessed in 95 Norwegian adolescents, who participated in the RHINESSA generation study. Symptoms of allergic disease were assessed by an interviewer-led questionnaire.

Results

Atopic sensitization was found in 33 (34.7%) of the adolescents. Symptomatic allergic disease was found in 11 (33.3%) of tho

SUBMITTER: Konigstein K 

PROVIDER: S-EPMC6695156 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature