Assessing the variability and predictability of adipokines (adiponectin, leptin, resistin and their ratios) in non-obese and obese women with anovulatory polycystic ovary syndrome.

ABSTRACT:

Objectives

To assess the variability and predictability of adiponectin, leptin, resistin and their ratios in non-obese and obese women with anovulatory polycystic ovary syndrome (aPCOS).

Results

A total of 52 ovulatory controls (mean age = 31.63 ± 4.88 years, BMI = 25.33 ± 2.68 kg/m²); 54 non-obese (mean age = 32.11 ± 4.25 years, BMI = 25.72 ± 2.95 kg/m²) and 50 obese women with aPCOS (mean age = 33.64 ± 4.14 years, BMI = 39.19 ± 2.99 kg/m²) were recruited. The aPCOS group had lower adiponectin [13.0 (10.49-16.59) vs 18.42 (15.72-19.92) µg/ml, p < 0.0001], adiponectin: leptin ratio (A:L) [0.60 (0.35-0.88) vs 1.19 (0.92-1.37), p < 0.0001], and adiponectin: resistin ratio (A:R) [0.30 (0.21-0.43) vs 0.42 (0.32-0.62), p < 0.0001] but a higher lep

SUBMITTER: Obirikorang C 

PROVIDER: S-EPMC6696689 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature