Burden of laboratory-confirmed shigellosis infections in Guatemala 2007-2012: results from a population-based surveillance system.

ABSTRACT:

Background

We describe the epidemiology and antimicrobial susceptibility patterns of culture-confirmed Shigella infections in facility-based surveillance sites in Guatemala. Current studies using quantitative molecular diagnostics suggest Shigella may contribute most to the global diarrheal disease burden. Since identification of Shigella requires culturing techniques using stool specimens and few laboratories in Guatemala routinely culture for this pathogen, little is known about the true burden of Shigella in Guatemala or, importantly, the antimicrobial resistance patterns.

Methods

Clinical, epidemiological, and laboratory data were collected on 5399 patients with acute diarrhea (≥3 loose stools in 24 h) from June 2007-August 2012. Multidrug resistance (MDR) was defined as

SUBMITTER: Hegde S 

PROVIDER: S-EPMC6696707 | biostudies-literature | 2019 May

REPOSITORIES: biostudies-literature