Dataset Information

Limitations of Fat-Free Mass for the Assessment of Muscle Mass in Obesity.

ABSTRACT:

Background

A high amount of adipose tissue limits the accuracy of methods for body composition analysis in obesity.

Objectives

The aim was to quantify and explain differences in fat-free mass (FFM) (as an index of skeletal muscle mass, SMM) measured with bioelectrical impedance analysis (BIA), dual energy X-ray absorptiometry (DXA), air displacement plethysmography (ADP), and deuterium dilution in comparison to multicompartment models, and to improve the results of BIA for obese subjects.

Methods

In 175 healthy subjects (87 men and 88 women, BMI 20-43.3 kg/m2, 18-65 years), FFM measured by these methods was compared with results from a 3- (3C) and a 4-compartment (4C) model. FFM4C was compared with SMM measured by magnetic resonance imaging.