Epidemiology of Hospital-Onset Versus Community-Onset Sepsis in U.S. Hospitals and Association With Mortality: A Retrospective Analysis Using Electronic Clinical Data.

ABSTRACT:

Objectives

Prior studies have reported that hospital-onset sepsis is associated with higher mortality rates than community-onset sepsis. Most studies, however, have used inconsistent case-finding methods and applied limited risk-adjustment for potential confounders. We used consistent sepsis criteria and detailed electronic clinical data to elucidate the epidemiology and mortality associated with hospital-onset sepsis.

Design

Retrospective cohort study.

Setting

136 U.S. hospitals in the Cerner HealthFacts dataset.

Patients

Adults hospitalized in 2009-2015.

Interventions

None.

Measurements and main results

We identified sepsis using Centers for Disease Control and Prevention Adult Sepsis Event criteria and estimated the risk of in-hospital death fo

SUBMITTER: Rhee C 

PROVIDER: S-EPMC6697188 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature