ENose analysis of volatile chemicals from dogs naturally infected with Leishmania infantum in Brazil.

ABSTRACT:

Background

Visceral leishmaniasis (VL) in Brazil is a neglected, vector-borne, tropical parasitic disease that is responsible for several thousand human deaths every year. The transmission route involves sand flies becoming infected after feeding on infected reservoir host, mainly dogs, and then transmitting the Leishmania infantum parasites while feeding on humans. A major component of the VL control effort is the identification and euthanasia of infected dogs to remove them as a source of infection. A rapid, non-invasive, point-of-care device able to differentiate between the odours of infected and uninfected dogs may contribute towards the accurate diagnosis of canine VL.

Methodology/principal findings

We analysed the headspace volatile chemicals from the hair of two grou

SUBMITTER: Staniek ME 

PROVIDER: S-EPMC6697360 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature