Ontology highlight
ABSTRACT:
SUBMITTER: Serra-Peinado C
PROVIDER: S-EPMC6697690 | biostudies-literature | 2019 Aug
REPOSITORIES: biostudies-literature
Nature communications 20190816 1
The identification of exclusive markers to target HIV-reservoir cells will represent a significant advance in the search for therapies to cure HIV. Here, we identify the B lymphocyte antigen CD20 as a marker for HIV-infected cells in vitro and in vivo. The CD20 molecule is dimly expressed in a subpopulation of CD4-positive (CD4<sup>+</sup>) T lymphocytes from blood, with high levels of cell activation and heterogeneous memory phenotypes. In lymph node samples from infected patients, CD20 is pres ...[more]