VIST - a Variant-Information Search Tool for precision oncology.

ABSTRACT:

Background

Diagnosis and treatment decisions in cancer increasingly depend on a detailed analysis of the mutational status of a patient's genome. This analysis relies on previously published information regarding the association of variations to disease progression and possible interventions. Clinicians to a large degree use biomedical search engines to obtain such information; however, the vast majority of scientific publications focus on basic science and have no direct clinical impact. We develop the Variant-Information Search Tool (VIST), a search engine designed for the targeted search of clinically relevant publications given an oncological mutation profile.

Results

VIST indexes all PubMed abstracts and content from ClinicalTrials.gov. It applies advanced text mining t

SUBMITTER: Seva J 

PROVIDER: S-EPMC6697931 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature