Using neighborhood gray tone difference matrix texture features on dual time point PET/CT images to differentiate malignant from benign FDG-avid solitary pulmonary nodules.

ABSTRACT:

Objective

Lung cancer usually presents as a solitary pulmonary nodule (SPN) on diagnostic imaging during the early stages of the disease. Since the early diagnosis of lung cancer is very important for treatment, the accurate diagnosis of SPNs has much importance. The aim of this study was to evaluate the discriminant power of dual time point imaging (DTPI) PET/CT in the differentiation of malignant and benign FDG-avid solitary pulmonary nodules by using neighborhood gray-tone difference matrix (NGTDM) texture features.

Methods

Retrospective analysis was carried out on 116 patients with SPNs (35 benign and 81 malignant) who had DTPI ¹⁸F-FDG PET/CT between January 2005 and May 2015. Both PET and CT images were acquired at 1 h and 3 h after injection. The SUV_max

SUBMITTER: Chen S 

PROVIDER: S-EPMC6697997 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature