Patient-reported Quality of Life Following Stereotactic Body Radiotherapy and Conventionally Fractionated External Beam Radiotherapy Compared with Active Surveillance Among Men with Localized Prostate Cancer.

ABSTRACT:

Background

Evidence supporting the efficacy of stereotactic body radiotherapy (SBRT) for localized prostate cancer is accumulating, but comparative studies of patient-reported quality of life (QOL) following SBRT versus conventionally fractionated external beam radiotherapy (EBRT) or active surveillance (AS) are limited.

Objective

To compare QOL of patients pursuing SBRT and EBRT versus AS.

Design, setting, and participants

A population-based cohort of 680 men with newly diagnosed localized prostate cancer was prospectively enrolled from 2011 to 2013.

Intervention

SBRT, EBRT without androgen deprivation therapy, or AS.

Outcome measurements and statistical analysis

QOL was prospectively assessed before treatment (baseline), and at 3, 12, and 24mo after tr

SUBMITTER: Moon DH 

PROVIDER: S-EPMC6698206 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature