Comparison of the effect of sevoflurane or propofol anesthesia on the regional cerebral oxygen saturation in patients undergoing carotid endarterectomy: a prospective, randomized controlled study.

ABSTRACT:

Background

The monitoring of regional cerebral oxygen saturation (SrO₂) using near-infrared spectroscopy is useful method to detect cerebral ischemia during. Sevoflurane and propofol decrease cerebral metabolic rate (CMRO₂) in a similar manner, but the effects on the cerebral blood flow (CBF) are different. We hypothesized that the effects of sevoflurane and propofol on SrO₂ were different in patients with deficits of CBF. This study compared the effect of sevoflurane and propofol on SrO₂ of patients undergoing cerebral endarterectomy (CEA).

Method

Patients undergoing CEA were randomly assigned to the sevoflurane or propofol group (n = 74). The experiment was preceded in 2 stages based on carotid artery clamping. The first stage wa

SUBMITTER: Park S 

PROVIDER: S-EPMC6698343 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature