Anterior hippocampal volume predicts affect-focused psychotherapy outcome.

ABSTRACT:

Background

The hippocampus plays an important role in psychopathology and treatment outcome. While posterior hippocampus (PH) may be crucial for the learning process that exposure-based treatments require, affect-focused treatments might preferentially engage anterior hippocampus (AH). Previous studies have distinguished the different functions of these hippocampal sub-regions in memory, learning, and emotional processes, but not in treatment outcome. Examining two independent clinical trials, we hypothesized that anterior hippocampal volume would predict outcome of affect-focused treatment outcome [Interpersonal Psychotherapy (IPT); Panic-Focused Psychodynamic Psychotherapy (PFPP)], whereas posterior hippocampal volume would predict exposure-based treatment outcome [Prolonged Expo

SUBMITTER: Suarez-Jimenez B 

PROVIDER: S-EPMC6698431 | biostudies-literature | 2020 Feb

REPOSITORIES: biostudies-literature