Systematic review with meta-analysis: faecal diversion for management of perianal Crohn's disease.

ABSTRACT:

Background

Temporary faecal diversion is sometimes used for management of refractory perianal Crohn's disease (CD) with variable success.

Aims

To perform a systematic review with meta-analysis to evaluate the effectiveness, long-term outcomes and factors associated with success of temporary faecal diversion for perianal CD.

Methods

Through a systematic literature review through 15 July 2015, we identified 16 cohort studies (556 patients) reporting outcomes after temporary faecal diversion. We estimated pooled rates [with 95% confidence interval (CI)] of early clinical response, attempted and successful restoration of bowel continuity after temporary faecal diversion (without symptomatic relapse), and rates of re-diversion (in patients with attempted restoration) and p

SUBMITTER: Singh S 

PROVIDER: S-EPMC6698449 | biostudies-literature | 2015 Oct

REPOSITORIES: biostudies-literature