Three-dimensional pattern of extraretinal neovascular development in retinopathy of prematurity.

ABSTRACT:

Background

The application of three-dimensional (3D) visualization techniques to evaluate the earliest visible onset of abnormal retinal vascular development in preterm infants with retinopathy of prematurity (ROP), using bedside non-contact optical coherence tomography (OCT) imaging to characterize morphology and sequential structural changes of abnormal extraretinal neovascularization.

Methods

Thirty-one preterm infants undergoing routine ROP screening with written informed consent for research imaging were enrolled in this prospective observational study. We imaged the macula and temporal periphery of preterm infants using a handheld OCT system (Envisu 2300 or handheld swept-source research system). The scans obtained were segmented and, using enhanced ray casting, were c

SUBMITTER: Mangalesh S 

PROVIDER: S-EPMC6698900 | biostudies-literature | 2019 Apr

REPOSITORIES: biostudies-literature