Western oropharyngeal and gut microbial profiles are associated with allergic conditions in Chinese immigrant children.

ABSTRACT:

Background

The allergy epidemic resulting from western environment/lifestyles is potentially due to modifications of the human microbiome. Therefore, it is of interest to study immigrants living in a western environment as well as their counterparts in the country of origin to understand differences in their microbiomes and health status.

Methods

We investigated 58 Australian Chinese (AC) children from Perth, Western Australia as well as 63 Chinese-born Chinese (CC) children from a city in China. Oropharyngeal (OP) and fecal samples were collected. To assess the microbiomes, 16s ribosomal RNA (rRNA) sequencing for variable regions V3 and V4 was used. Skin prick tests (SPT) were performed to measure the children's atopic status. Information on food allergy and wheezing were a

SUBMITTER: Guo J 

PROVIDER: S-EPMC6699559 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature