Intravenous Tissue Plasminogen Activator in Stroke Mimics.

ABSTRACT:

Background

The necessity for rapid evaluation and treatment of acute ischemic stroke with intravenous tPA (tissue-type plasminogen activator) may increase the risk of administrating tPA to patients presenting with noncerebrovascular conditions that closely resemble stroke (stroke mimics). However, there are limited data on thrombolysis safety in stroke mimics.

Methods and results

Using data from the Get With The Guidelines-Stroke Registry, we identified 72 582 patients with suspected ischemic stroke treated with tPA from 485 US hospitals between January 2010 and December 2017. We documented the use of tPA in stroke mimics, defined as patients who present with stroke-like symptoms, but after workup are determined not to have suffered from a stroke or transient ischemic attack

SUBMITTER: Ali-Ahmed F 

PROVIDER: S-EPMC6699639 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature