Robust Non-Rigid Motion Compensation of Free-Breathing Myocardial Perfusion MRI Data.

ABSTRACT: Kinetic parameter values, such as myocardial perfusion, can be quantified from dynamic contrast-enhanced magnetic resonance imaging data using tracer-kinetic modeling. However, respiratory motion affects the accuracy of this process. Motion compensation of the image series is difficult due to the rapid local signal enhancement caused by the passing of the gadolinium-based contrast agent. This contrast enhancement invalidates the assumptions of the (global) cost functions traditionally used in intensity-based registrations. The algorithms are unable to distinguish whether the differences in signal intensity between frames are caused by the spatial motion artifacts or the local contrast enhancement. In order to address this problem, a fully automated motion compensation scheme is proposed, w

SUBMITTER: Scannell CM 

PROVIDER: S-EPMC6699991 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature