Multidimensional assessment of fatigue in patients with brain metastases before and after Gamma Knife radiosurgery.

ABSTRACT:

Purpose

Fatigue is a common and distressing symptom in cancer patients which negatively affects patients' daily functioning and health-related quality of life. The aim of this study was to assess multidimensional fatigue in patients with brain metastases (BM) before, and after Gamma Knife radiosurgery (GKRS).

Methods

Patients with BM, an expected survival > 3 months, and a Karnofsky Performance Status ≥ 70 and 104 Dutch non-cancer controls were recruited. The Multidimensional Fatigue Inventory (MFI), measuring general fatigue, physical fatigue, mental fatigue, reduced activity and reduced motivation, was used. Baseline levels of fatigue between patients and controls were compared using independent-samples t-tests. The course of fatigue over time, and clinical and psychologic

SUBMITTER: Verhaak E 

PROVIDER: S-EPMC6700236 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature