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Hepatitis C virus genotype affects survival in patients with hepatocellular carcinoma.


ABSTRACT:

Background

There is currently no evidence that hepatitis C virus (HCV) genotype affects survival in patients with hepatocellular carcinoma (HCC). This study aimed to investigate whether the HCV genotype affected the survival rate of patients with HCV-related HCC.

Methods

We performed a retrospective cohort study using the data of patients with HCV-related HCC evaluated at two centers in Korea between January 2005 and December 2016. Propensity score matching between genotype 2 patients and non-genotype 2 patients was performed to reduce bias.

Results

A total of 180 patients were enrolled. Of these, 86, 78, and 16 had genotype 1, genotype 2, and genotype 3 HCV-related HCC, respectively. The median age was 66.0 years, and the median overall survival was 28.6 months. In t

SUBMITTER: Park HK 

PROVIDER: S-EPMC6700836 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature

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