Characterization of the BspA and Pmp protein family of trichomonads.

ABSTRACT:

Background

Trichomonas vaginalis is a human-infecting trichomonad and as such the best studied and the only for which the full genome sequence is available considering its parasitic lifestyle, T. vaginalis encodes an unusually high number of proteins. Many gene families are massively expanded and some genes are speculated to have been acquired from prokaryotic sources. Among the latter are two gene families that harbour domains which share similarity with proteins of Bacteroidales/Spirochaetales and Chlamydiales: the BspA and the Pmp proteins, respectively.

Results

We sequenced the transcriptomes of five trichomonad species and screened for the presence of BspA and Pmp domain-containing proteins and characterized individual candidate proteins from both families in T. vaginal

SUBMITTER: Handrich MR 

PROVIDER: S-EPMC6701047 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature