Prognostic impact of alkaline phosphatase for in-hospital mortality in patients with acute coronary syndrome: a prospective cohort study in China.

ABSTRACT:

Objectives

Alkaline phosphatase (ALP) can promote vascular calcification, but the association between ALP and in-hospital mortality in patients with acute coronary syndrome (ACS) is not well defined.

Design

A prospective cohort study.

Setting and participants

A total of 6368 patients with ACS undergoing percutaneous coronary intervention (PCI) from 1 January 2010 to 31 December 2017 were analysed.

Main outcome measures

In-hospital mortality was used in this study.

Results

ALP was analysed both as a continuous variable and according to three categories. After multivariable adjustment, in-hospital mortality was significantly higher in Tertile 3 group (ALP＞85 U/L) (OR: 2.399, 95% CI 1.080 to 5.333, p=0.032), compared with other two groups (Tertile 1: ＜66 U/

SUBMITTER: Yu T 

PROVIDER: S-EPMC6701695 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature