Hepatic proteome network data in zebrafish (Danio rerio) liver following dieldrin exposure.

ABSTRACT: Dieldrin is an environmental contaminant that adversely affects aquatic organisms. The data presented in this study are proteomic data collected in liver of zebrafish that were exposed to the pesticide in a dietary exposure. For label free proteomics, data were collected with a quadrupole Time-of-Flight mass spectrometer and for iTRAQ proteomics, data were acquired using a hybrid quadrupole Orbitrap (Q Exactive) MS system. Using formic acid digestion and label free proteomics, 2,061 proteins were identified, and among those, 103 were differentially abundant (p < 0.05 in at least one dose). In addition, iTRAQ proteomics identified 722 proteins in the liver of zebrafish following dieldrin treatment. The label-free approach identified 21 proteins that followed a dose dependent response. Of th

SUBMITTER: Simmons DBD 

PROVIDER: S-EPMC6702387 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature