Individualised Approaches for Catheter Ablation of AF: Patient Selection and Procedural Endpoints.

ABSTRACT: Pulmonary vein isolation (PVI) is the cornerstone of AF ablation, but studies have reported improved efficacy with high rates of repeat procedures. Because of the large interindividual variability in the underlying electrical and anatomical substrate, achieving optimal outcomes requires an individualised approach. This includes optimal candidate selection as well as defined ablation strategies with objective procedure endpoints beyond PVI. Candidate selection is traditionally based on coarse and sometimes arbitrary clinical stratification such as AF type, but finer predictors of treatment efficacy including biomarkers, advanced imaging and electrocardiographic parameters have shown promise. Numerous ancillary ablation strategies beyond PVI have been investigated, but the absence of a clear

SUBMITTER: Johner N 

PROVIDER: S-EPMC6702473 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature