Genome-wide selection signatures analysis of litter size in Dazu black goats using single-nucleotide polymorphism.

ABSTRACT: Litter size is considered to be the most important index for estimating domestic animal productivity. The number of indigenous goats in China with higher litter sizes than those of commercial breeds in other countries may be helpful for accelerating genetic improvements in goat breeding. We performed a genome-wide selective sweep analysis of 31 Dazu black goats with extreme standard deviation in litter size within the third fetus to identify significant genomic regions and candidate genes through different analyses. The analysis identified a total of 33,917,703 variants, including 32,262,179 SNPs and 1,655,524 indels. In addition, two novel candidate genes (LRP1B and GLRB), which are related to litter size, were obtained with π, Tajima's D, πA/πB, and

SUBMITTER: E GX 

PROVIDER: S-EPMC6702510 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature