Association of single nucleotide polymorphisms in the fatty acid synthase, LOC514211, and fat mass and obesity-associated genes with milk traits in Indonesian-Holstein dairy cattle.

ABSTRACT:

Aim

The study aimed to identify fatty acid synthase (FASN), LOC514211, and fat mass and obesity-associated (FTO) gene polymorphisms and to investigate their associations with milk traits in an Indonesian-Holstein dairy cow population.

Materials and methods

A total of 100 Indonesian-Holstein cows consisting of 50 heads (0^th generation; G₀) and 50 heads of their daughters (1^st generation; G₁) were used. Polymerase chain reaction-restriction fragment length polymorphism was performed to genotype three single nucleotide polymorphisms: rs41919985 in the FASN gene, rs42688595 in the LOC514211 gene, and g.1371T>A in the FTO gene.

Results

FASN rs41919985 was associated with milk protein percentage (p<0.05), FTO g.1371T>A was associa

SUBMITTER: Rahayu AP 

PROVIDER: S-EPMC6702549 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature