A human subcortical network underlying social avoidance revealed by risky economic choices.

ABSTRACT: Social interactions have a major impact on well-being. While many individuals actively seek social situations, others avoid them, at great cost to their private and professional life. The neural mechanisms underlying individual differences in social approach or avoidance tendencies are poorly understood. Here we estimated people's subjective value of engaging in a social situation. In each trial, more or less socially anxious participants chose between an interaction with a human partner providing social feedback and a monetary amount. With increasing social anxiety, the subjective value of social engagement decreased; amygdala BOLD response during decision-making and when experiencing social feedback increased; ventral striatum BOLD response to positive social feedback decreased; and conn

SUBMITTER: Schultz J 

PROVIDER: S-EPMC6703852 | biostudies-literature | 2019 Jul

REPOSITORIES: biostudies-literature