Ascertainment of Aspirin Exposure Using Structured and Unstructured Large-scale Electronic Health Record Data.

ABSTRACT:

Background

Aspirin impacts risk for important outcomes such as cancer, cardiovascular disease, and gastrointestinal bleeding. However, ascertaining exposure to medications available both by prescription and over-the-counter such as aspirin for research and quality improvement purposes is a challenge.

Objectives

Develop and validate a strategy for ascertaining aspirin exposure, utilizing a combination of structured and unstructured data.

Research design

This is a retrospective cohort study.

Subjects

In total, 1,869,439 Veterans who underwent usual care colonoscopy 1999-2014 within the Department of Veterans Affairs.

Measures

Aspirin exposure and dose were obtained from an ascertainment strategy combining query of structured medication records available in

SUBMITTER: Bustamante R 

PROVIDER: S-EPMC6703965 | biostudies-literature | 2019 Oct

REPOSITORIES: biostudies-literature