Concordant systemic and local eosinophilia relates to poorer disease control in patients with nasal polyps.

ABSTRACT:

Background

Eosinophilic inflammation is a major phenotype associated with poorly controlled disease in nasal polyp patients. The difference between systemic and local eosinophilia in relation to disease control is poorly understood.

Objective

To explore whether blood and polyp tissue eosinophil numbers are independent risk factors for poor disease control in patients with nasal polyp.

Methods

By using the electronic medical records database and manual evaluation, 183 nasal polyp patients who had undergone endoscopic sinus surgery at least one year prior to the study with complete data of tissue specimens, baseline blood routine test, nasal endoscopy and sinus computed tomography, were identified and recruited to assess disease control based on the criteria of a Europe

SUBMITTER: Wang K 

PROVIDER: S-EPMC6704051 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature