Change in left atrial function predicts incident atrial fibrillation: the Multi-Ethnic Study of Atherosclerosis.

ABSTRACT:

Aims

Longitudinal change in left atrial (LA) structure and function could be helpful in predicting risk for incident atrial fibrillation (AF). We used cardiac magnetic resonance (CMR) imaging to explore the relationship between change in LA structure and function and incident AF in a multi-ethnic population free of clinical cardiovascular disease at baseline.

Methods and results

In the Multi-Ethnic Study of Atherosclerosis (MESA), 2338 participants, free at baseline of clinically recognized AF and cardiovascular disease, had LA volume and function assessed with CMR imaging, at baseline (2000-02), and at Exam 4 (2005-07) or 5 (2010-12). Free of AF, 124 participants developed AF over 3.8 ± 0.9 years (2015) following the second imaging. In adjusted Cox regression models, an ave

SUBMITTER: Lim DJ 

PROVIDER: S-EPMC6704390 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature