Biohybrid Electrospun Membrane for the Filtration of Ketoprofen Drug from Water.

ABSTRACT: A current challenge in materials science and biotechnology is to express a specific and controlled functionality on the large interfacial area of a nanostructured material to create smart biohybrid systems for targeted applications. Here, we report on a biohybrid system featuring poly(vinyl alcohol) as the supporting synthetic polymer and bovine serum albumin as the biofunctional element. The optimal processing conditions to produce these self-standing composite membranes are determined, and the composition and distribution of the bioactive agent within the polymeric matrices are analyzed. A post-processing cross-linking using glutaraldehyde enables this functional membrane to be used as a chemical filter in aqueous environments. By demonstrating that our mats can remove large amounts of k

SUBMITTER: Castagna R 

PROVIDER: S-EPMC6704435 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature