Association of Thyroid Function Test Abnormalities and Thyroid Autoimmunity With Preterm Birth: A Systematic Review and Meta-analysis.

ABSTRACT:

Importance

Maternal hypothyroidism and hyperthyroidism are risk factors for preterm birth. Milder thyroid function test abnormalities and thyroid autoimmunity are more prevalent, but it remains controversial if these are associated with preterm birth.

Objective

To study if maternal thyroid function test abnormalities and thyroid autoimmunity are risk factors for preterm birth.

Data sources and study selection

Studies were identified through a search of the Ovid MEDLINE, EMBASE, Web of Science, the Cochrane Central Register of Controlled Trials, and Google Scholar databases from inception to March 18, 2018, and by publishing open invitations in relevant journals. Data sets from published and unpublished prospective cohort studies with data on thyroid function tests (th

SUBMITTER: Consortium on Thyroid and Pregnancy—Study Group on Preterm Birth 

PROVIDER: S-EPMC6704759 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature