A Neuromorphic Prosthesis to Restore Communication in Neuronal Networks.

ABSTRACT: Recent advances in bioelectronics and neural engineering allowed the development of brain machine interfaces and neuroprostheses, capable of facilitating or recovering functionality in people with neurological disability. To realize energy-efficient and real-time capable devices, neuromorphic computing systems are envisaged as the core of next-generation systems for brain repair. We demonstrate here a real-time hardware neuromorphic prosthesis to restore bidirectional interactions between two neuronal populations, even when one is damaged or missing. We used in vitro modular cell cultures to mimic the mutual interaction between neuronal assemblies and created a focal lesion to functionally disconnect the two populations. Then, we employed our neuromorphic prosthesis for bidirectional bridg

SUBMITTER: Buccelli S 

PROVIDER: S-EPMC6706626 | biostudies-literature | 2019 Sep

REPOSITORIES: biostudies-literature