Graphene Oxide-Based Dispersive-Solid Phase Extraction for Preconcentration and Determination of Ampicillin Sodium and Clindamycin Hydrochloride Antibiotics in Environmental Water Samples Followed by HPLC-UV Detection.

ABSTRACT: In this work, a reusable graphene oxide (GO) based dispersive-solid phase extraction (d-SPE) was synthesized and used for the analysis of trace ampicillin sodium (AMP) and clindamycin hydrochloride (CLI) in water samples followed by high performance liquid chromatography-UV detection (HPLC-UV). Batch experiments were conducted to investigate the effects of pH and volume of the sample solution, contact time, adsorption isotherms, temperature, and desorption conditions. The maximum adsorption capacities of AMP and CLI on GO nanosheets were found to be 33.33 mg g^-1 and 47 mg g^-1, respectively. The adsorption isotherm data can be well fitted by Temkin (AMP and CLI) and Freundlich (AMP), and the adsorption process followed the pseudo-second-order model. The thermodynamic p

SUBMITTER: Mohammad Nejad L 

PROVIDER: S-EPMC6706713 | biostudies-literature | 2019

REPOSITORIES: biostudies-literature