Would ivermectin for malaria control be beneficial in onchocerciasis-endemic regions?

ABSTRACT:

Background

There is accumulating evidence supporting the use of ivermectin as a malaria control tool. Recent findings from the repeat ivermectin mass drug administrations for control of malaria trial demonstrated a reduced incidence of malaria in villages which received repeated ivermectin mass drug administration (MDA; six doses) compared to those who had only one round of ivermectin. Several other studies investigating the benefits of ivermectin for malaria purposes are ongoing/planned.

Main text

While ivermectin MDA offers promising perspectives in the fight against malaria, we highlight the added benefits and anticipated challenges of conducting future studies in onchocerciasis-endemic regions, which are confronted with a substantial disease burden including onchocercias

SUBMITTER: Siewe Fodjo JN 

PROVIDER: S-EPMC6706915 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature